Review 02 Question Lock

Purpose

Turn a broad direction into a review question that can guide search, screening, evidence synthesis, and writing.

Required Inputs

• Project brief from $review-01-project-init.
• User preference on review type if available.
• Known constraints: deadline, target journal tier, disease area, model system, or clinical population.

Output

Create 01_question_scope/question_lock.md with:

• One primary question.
• Up to three secondary questions.
• PICO/PECO/PCC table when applicable.
• Inclusion boundary and exclusion boundary.
• Three candidate titles: conservative, balanced, high-impact.
• Recommended final choice with rationale.

Completion Gate

Pass only when the final question is narrow enough to generate database-specific search strings and broad enough to support a full review.

Stop Rules

Do not claim novelty. Phrase gaps as "candidate gap requiring literature verification" until search evidence is available.